Red Sox second baseman Dustin Pedroia exited Friday night’s 3-2 win in the top of the 10th with a right hand contusion.

NCAA tournament play opened Friday with a day full of upsets, drama and dominant pitching performances as 64 teams began their quest to reach the College World Series.

Mark Appel, ranked No. 14 on MLBPipeline.com’s Top 100 Prospects list, is now back with Lancaster and scheduled to make his first start in a month Saturday against Rancho Cucamonga at 9 p.m. ET. The Quakes will counter with left-hander Julio Urias, ranked No. 53 on the Top 100.

Red Sox manager John Farrell was ejected after Rays starter David Price hit David Ortiz in the first inning. Bench coach Torey Lovullo was ejected after Mike Carp was hit by Price in the fourth. Red Sox righty Brandon Workman was ejected after he threw behind Evan Longoria in the sixth, and because of the prior warnings, that made third-base coach Brian Butterfield an automatic ejection as acting manager.

Thanks to a dropped pop-up by Chris Young in the bottom of the 14th that gave way to a game-winning hit by Reid Brignac, Philadelphia managed a marathon 6-5 victory at Citizens Bank Park on Friday night.

Madison Bumgarner allowed three hits in seven shutout innings and struck out 10 in Friday’s 9-4 victory over the Cardinals. Bumgarner received ample offensive support, including Hunter Pence’s three-run homer off Adam Wainwright. The St. Louis ace allowed seven runs and eight hits in 4 1/3 innings.

Facing former teammate Bronson Arroyo, the Reds used a four-run second inning — featuring Devin Mesoraco’s grand slam — en route to a 6-4 victory over the D-backs at Chase Field on Friday.

Friday night, on the road, the Giants were facing the best opposition the National League could produce in 2013. And they were facing one of the very best pitchers in the game. Still, the Giants dominated the game in every conceivable way.

The Red Sox had a second consecutive walk-off celebration on Friday night at Fenway Park, this one thanks to a game-ending triple by A.J. Pierzynski that capped an emotional 3-2, 10-inning victory over the Rays.

Cardinals top prospect Oscar Taveras is on his way to St. Louis. Taveras, ranked as the No. 2 prospect in baseball, has been promoted and is headed to St. Louis in time for Saturday’s game against the Giants.

Ryan Braun’s opposite-field home run started a five-run first inning in an 11-5 Brewers win over the Cubs — a rout that left the Brewers on the verge of setting a franchise record for offense.

Brett Oberholtzer has seen nothing but victories since he rejoined the rotation Saturday in Seattle, and he pitched the Astros to their seventh win in a row in Friday night’s Civil Rights Game by holding the Orioles to four hits and one run in seven innings in a 2-1 decision before 38,482 fans at Minute Maid Park.

For the second consecutive night, Jose Bautista threw out a runner at first base on a ball hit to right field — this time nabbing Omar Infante — in the Blue Jays’ 6-1 loss to the Royals on Friday.

For all his eccentric moments, in his time as owner of the A’s, which he brought from Kansas City to Oakland, Charlie Finley put together a franchise that won five consecutive AL West titles (1971-75) and three consecutive World Series (1972-74). The A’s are celebrating the 40th anniversary of Finley’s final world championship this weekend.

Lorenzo Cain and Alex Gordon belted two-run homers, while Jason Vargas logged seven strikeouts as the Royals posted a 6-1 win over the Blue Jays on Friday night at Rogers Centre.

The Indians have found their stopper in right-hander Corey Kluber. Two months into this season, Cleveland is starting to believe that it might also have a new ace on its hands. On Friday night, Kluber took the hill at Progressive Field and overpowered the Rockies in a 5-2 victory, ending the Tribe’s four-game losing streak.

The Nationals offense showed signs of life on Friday night, as it collected 15 hits and pounded the Rangers, 9-2, at Nationals Park.