Led by the game’s top two prospects — Dodgers shortstop Corey Seager and Twins center fielder Byron Buxton — dozens of players on teams’ Top 30 Prospects lists are beginning the 2016 season in the big leagues.

Astros manager A.J. Hinch ended weeks of speculation Monday morning by announcing veteran right-hander Luke Gregerson would open the season as the team’s “primary closer,” meaning newcomer Ken Giles will pitch in different roles to begin the season.

In the first game of the 2016 season, Pirates southpaw Francisco Liriano — making his third straight Opening Day start for the team — silencing the Cardinals’ offense to the tune of three hits and 10 strikeouts over six scoreless innings at PNC Park.

Welcome to Opening Day — the best day of the year. We love its symbolism and its vibe. We love the sense of optimism that arrives along with it, and the endless possibilities of another season.

Edinson Volquez gave up two hits over six shutout innings and the reigning World Series champion Royals held off the Mets, 4-3, on Sunday night in front of a sold-out crowd at Kauffman Stadium in the season opener for both teams.

A rundown of the top GIFs of the night, courtesy of @MLBGIFs, from Opening Day around Major League Baseball.

From Opening Day through the All-Star Game in San Diego through the final pitch of the 112th World Series, it’s time again for MLB.TV.

Eight singles here, a couple of walks there, an error and an unearned run added up to an early exit and a frustrating defeat for Matt Harvey on Sunday night.

Hey, the Royals are proud of that World Series championship they won last November, the one that ended the franchise’s 30-year drought and reaffirmed Kansas City’s status as one of the game’s most energized baseball cities. It’s just that instead of looking back they want to focus on what’s ahead.

Nothing like opening the season by walking into a tense, game-on-the-line situation. But that’s how Royals right-hander Luke Hochevar opened his 2016 season, facing the Mets’ Asdrubal Cabrera with two outs and the tying run in scoring position in the eighth inning.

A routine play in the first inning of Sunday’s Opening Night game became anything but when Yoenis Cespedes settled under the liner and clamped his glove shut, only to watch the ball deflect off the leather and fall to the turf.

The Arizona D-backs included Ender Inciarte in the December trade for Shelby Miller, because they were confident enough in their outfield depth to part with someone who played more than 1,000 combined defensive innings across the outfield in 2015.

A sold-out crowd at Kauffman Stadium ushered in the new season by honoring the Royals’ 2015 run to a World Series championship in pregame ceremonies.

David Wright’s appearance on Sunday night at Kauffman Stadium marked his 12th consecutive Opening Day start with the Mets, passing Bud Harrelson and Tom Seaver for the most in franchise history.

From the beginning of the MLB season to another dominant UConn performance to the unlikely emergence of Jim Herman, Sunday was memorable.

The Pirates have agreed to terms with outfielder Gregory Polanco on a five-year contract extension that includes two club options, an industry source confirmed to MLB.com on Sunday.

The second time around in the rugged American League East is not so lovelier, as the melody goes. Since 2000, only the Yankees have won back-to-back titles and the last time they did, it was 2011-12.