David Ortiz is officially in that zone — the one in which he seems capable of hitting the ball over the fence every time he comes to the plate. The big slugger walloped two more homers to lead the Red Sox to a 9-4 victory over the Twins on Wednesday night at Target Field.

Offensive production has come in spurts for the Indians so far this season. On Wednesday night, the runs came gushing out in an overwhelming 15-4 rout over the Blue Jays at Rogers Centre.

Francisco Liriano’s arduous quest for his first win of 2014 continues, but his offense made sure Wednesday night’s performance would not be in vain as the Pirates rallied late for a 4-1 victory at Miller Park.

The investment that the Yankees made in Masahiro Tanaka has so far proven to be worth its weight in yen. Just when they needed it the most, the right-hander shut down the Mets, 4-0, on Wednesday night at Citi Field, giving the American League club its first win in a Subway Series game since 2012, and first in Queens since 2011.

CC Sabathia visited with Dr. James Andrews this week for an additional opinion on his troublesome right knee, and the noted orthopedist discovered “degenerative changes” in the knee, general manager Brian Cashman told reporters at Citi Field on Wednesday.

Masahiro Tanaka turned in a lights-out performance in his Subway Series debut, permitting just four hits in his first career shutout as the Yankees posted a 4-0 victory over the Mets on Wednesday at Citi Field.

The Mets on Wednesday outrighted veteran reliever Kyle Farnsworth, who was the team’s closer as recently as Monday — and who was caught off-guard by the move. “I am very bitter right now,” Farnsworth said.

The Blue Jays brought infielder Steve Tolleson in to pitch in the top of the ninth inning in Wednesday’s 15-4 loss to the Indians. In doing so, he became the seventh position player in Toronto history to take the mound. Jeff Mathis was the last to do so, in 2012.

Gregor Blanco scored three runs and stole three bases Wednesday, complementing home runs by Hunter Pence, Michael Morse and Brandon Crawford as the Giants subdued the Atlanta Braves, 10-4.

MLB has given David Ortiz a single from last Friday’s game between the Red Sox and Rangers. Imagine what fodder this would have been for the blogosphere on two continents if Yu Darvish had gotten Ortiz out in the ninth inning, setting off a celebration in Arlington and Tokyo, only to learn five days later that he had a one-hitter, not a no-no.

In light of the injury to Jose Fernandez, the Marlins have been in the market for a pitcher with big league experience. They found an option in left-hander Randy Wolf.

Jake Odorizzi’s quality start helped lift the Rays to a 2-0 win over the Mariners on Wednesday afternoon at Safeco Field. Odorizzi held the Mariners hitless through 5 2/3 innings before James Jones singled.

The Cardinals recalled second baseman Kolten Wong from Memphis and optioned infielder Greg Garcia to the Triple-A club on Wednesday.

Jon Singleton, the slugging first baseman who’s having a strong season at Triple-A Oklahoma City, will join the Astros at some point this season, GM Jeff Luhnow said Wednesday, but when exactly the Astros’ No. 4 prospect will get called up remains a mystery.

Jose Abreu crushed a three-run homer, his Major League-leading 15th, with one out in the eighth to rally the White Sox to a 4-2 victory over the A’s on Wednesday in Oakland.

Two-run singles by Ian Desmond and Tyler Moore in the top of the ninth inning helped the Nationals defeat the D-backs, 5-1, at Chase Field on Wednesday afternoon.

Jose Fernandez, along with his family, is weighing how to move forward in regard to his pending surgery. “I think it’s inevitable,” said Michael Hill, president of baseball operations. “He has to have surgery. It’s just a matter of when he comes to grips … and makes that decision.”