Dallas Keuchel suffered his first defeat at Minute Maid Park in a span of 23 regular-season starts on Monday, allowing five runs, five walks and seven hits in 4 1/3 innings in a 6-2 loss to the Twins. Twins rookie Jose Berrios, making the second start of his career, held the Astros to three hits and two runs in 5 1/3 innings for his first Major League win.