Darwin Barney hit a two-run walk-off home run off Padres right-hander Dale Thayer, as the Cubs beat the Padres, 8-6, Wednesday at Wrigley Field to complete a three-game sweep.

Dustin Pedroia's best-case scenario would probably entail a return to the starting lineup when the Red Sox return from their short weekend road trip to Toronto and host the Orioles on Tuesday.

In an appearance that had light moments but ended up being germane to the case, former Major League catcher Charlie O'Brien testified Wednesday that vitamin B12 shots were made readily available to players in Toronto, supporting a claim made by Roger Clemens that is a key element in Clemens' federal perjury trial.

White Sox left-hander Jose Quintana and manager Robin Ventura were ejected during the fourth inning of Wednesday's 4-3 win against the Rays at Tropicana Field after Quintana threw behind Tampa Bay outfielder Ben Zobrist.

Not only can fans cast their votes up to 25 times for starters in the 2012 All-Star Game, but they can also become campaign managers for their favorite Pirates as part of the Tweet the Vote movement.

Five starts after Doug Fister came back from the disabled list, he's back on the DL with the same left side strain that sidelined him for a month. But realistically, manager Jim Leyland said, he had been battling the side injury for most of that time.

The Phillies said Ryan Howard is making progress in Clearwater, Fla., but don't expect him back in the lineup before the end of June.

On Wednesday, Charlie Manuel became the first active Major League Baseball manager to visit the MLB Fan Cave since it was opened for the 2011 season. He regaled the just-reduced group of Cave Dwellers with funny stories, reported that Ryan Howard should be back before the All-Star break, answered skeptics who say Roy Halladay's injury is the last straw, taped an upcoming video with Shane Victorino where the skipper reads his player's latest tweets, and made another pretty good case for himself as arguably the coolest manager in the game.

Along with belting 11 home runs in the month, Giancarlo Stanton has driven in 29 runs after his RBI single against the Nationals on Wednesday.

Left-hander Jose Quintana and manager Robin Ventura were ejected in the fourth inning, but the White Sox held on to beat the Rays, 4-3, to push their season-high winning streak to eight games.

In the past 24-plus hours since MLB.com reported Tuesday that he saved a choking victim by performing the Heimlich Maneuver, Reds third baseman Todd Frazier has been a man in demand.

The Royals' 6-3 win over the Indians in the rubber game on Wednesday ensured a series win, a winning road trip and the franchise's first winning month of May since 2000.

White Sox center fielder Alejandro De Aza left Wednesday's 4-3 win against the Rays at Tropicana Field in the sixth inning after being hit on the right leg while diving back to second base.

Mets COO Jeff Wilpon reiterated general manager Sandy Alderson's call for patience on Wednesday, saying that extension talks with third baseman David Wright are not necessarily imminent.

Travis Snider, whose injured right wrist has kept him out of action, has yet to make progress, and he was sent to the Minor League complex for more rehab.

Nick Markakis was not in Baltimore's lineup for Wednesday's series finale against Toronto because of a sore

right wrist.

The Indians placed designated hitter Travis Hafner on the 15-day disabled list Wednesday with inflammation in his right knee, retroactive to Thursday.