The curse of 100 losses was officially avoided by the White Sox on Saturday night courtesy of their 6-5 victory against the Royals at U.S. Cellular Field.

Andy Pettitte held the glove high in front of his face, his eyes intently peering over the black leather for the final time. In this season of farewells, the Yankees left-hander closed out his career with one more vintage performance. Facing the only other club he has pitched for, Pettitte held the Astros to five hits while hurling the 26th complete game of his career in the Yankees’ 2-1 victory over Houston on Saturday night at Minute Maid Park.

Giancarlo Stanton blistered an RBI single to center in the 10th inning that gave the Marlins a 2-1 win over the Tigers on Saturday night in front of 28,750 at Marlins Park.

On Saturday, musicians such as Bono and Stevie Wonder, and world leaders, including U.N. Secretary-General Ban Ki-moon and Liberian President Ellen Johnson Sirleaf, came together at the Global Citizen Festival in New York’s Central Park to empower, inspire and unite the global community to work toward an end to poverty.

Moments after they started Saturday night’s game against the Orioles, the Red Sox clinched the best record in the American League, meaning they will have home-field advantage for every postseason series they play. Home-field advantage officially went to Boston once the Athletics lost to the Mariners in Seattle on Saturday.

With two days remaining, the AL Wild Card race for two spots has three teams within a game of each other, both leagues await a top seed and the NL Wild Card Game still doesn’t have a home.

Right-hander Adam Wainwright was solid in picking up his 19th victory and Matt Holliday’s early two-run jack propelled the Cardinals to a 6-2 win over the Cubs on Saturday.

Jimmy Nelson was solid in his first Major League start and the Brewers overcame a blown save to beat the Mets, 4-2, in 10 innings on Saturday at Citi Field. Former Mets prospect Carlos Gomez led the way for Milwaukee with four hits, including a home run in the fourth inning and a go-ahead single in the 10th off Scott Atchison.

Major League Baseball announced Saturday the potential tiebreaker schedule should the American League Wild Card race end in a draw.

On Saturday, the Tribe used a strong outing from lefty Scott Kazmir to roll to a 5-1 victory over the Twins, extending the Indians’ winning streak to a season-high nine games. With the win, Cleveland moved into sole possession of the American League’s top Wild Card spot.

Jarrod Parker gave up a pair of home runs to Mariners rookie shortstop Brad Miller, including a grand slam, as the division-champion A’s fell by a 7-5 margin on Saturday.

Unwilling to let Hunter Pence get the faintest whiff of free agency, the Giants announced they agreed with him on a five-year contract extension Saturday, accomplishing their top offseason priority a day before the regular season ends.

2013 Major League Baseball postseason schedule and matchups

Saying that he will be “fighting for my life and my whole legacy,” Alex Rodriguez said that he is “excited” to begin his appeal of a 211-game drug suspension. The appeal process of Rodriguez’s suspension is scheduled to begin on Monday at Major League Baseball’s offices in New York. Rodriguez can turn his attention to his legal situation because he said on Saturday that he will not play this weekend against the Astros due to lingering soreness in his legs.

With Mat Latos battling arm soreness and Sunday’s game now inconsequential, Reds manager Dusty Baker announced after Saturday’s 8-3 loss that Johnny Cueto will start Tuesday’s National League Wild Card Game.

Mariano Rivera has thrown his final pitch. The all-time saves leader said on Saturday that he has decided to allow the last moment of his playing career to be an emotional embrace on the Yankee Stadium mound. Rivera said that he was blessed with the ideal conclusion to his career on Thursday, when the 43-year-old closer retired all four Rays batters he faced and tearfully handed the ball off to longtime teammates Andy Pettitte and Derek Jeter.

The Pirates will host the Cincinnati Reds in the National League Wild Card Game on Tuesday, a date arranged two-thirds of the way through the regular-season concluding set here dubbed the Dating Games.