Right-hander Jeremy Guthrie tossed six shutout innings and Eric Hosmer scored twice and drove in a run as the Royals took a 7-1 win over the Reds on Wednesday night in front of 30,450 at Kauffman Stadium.

Pitching and defense ruled the day for both clubs on Wednesday night, but the Rangers got just enough out of spot starter Phil Klein and their bullpen to edge out a 2-1 victory over the Red Sox at Fenway Park.

It’s been a rough week for Bryce Harper when it comes to umpires. In Wednesday’s 3-2 victory over the Yankees, Harper and manager Matt Williams were ejected in the third inning.

Nick Castellanos awakened a Tigers offense that had been dormant all series with a bases-clearing triple in the eighth inning, breaking open a pitching duel and helping Detroit avoid a series sweep to the Brewers with a 5-2 win on Wednesday night at Comerica Park.

Williams Perez impressed in his first Major League start for the Braves, striking out seven and allowing one run over five innings to help the Rays claim a 2-1 win on Wednesday night.

Marc Krauss hit the go-ahead double in the seventh inning to back a quality start by right-hander Jered Weaver in the Angels’ 4-3 victory over the Blue Jays on Wednesday night at Rogers Centre.

Shaun Marcum, making his first big league start since 2013, worked six-plus innings and the Indians snapped a tie with a three-run seventh en route to a 4-3 victory over the White Sox on Wednesday night in Chicago.

Jordan Zimmermann’s Wednesday night outing against the Yankees did not start as he hoped it would. Brett Gardner and Carlos Beltran, the first two batters he faced, both hit safely and scored. After that, however, Zimmermann was brilliant.

After laboring to score one run over 14 innings in the series opener against the Mets, the Cardinals put together two of their biggest offensive performances of the season to ensure at least a series split.

Angels first baseman Albert Pujols left Wednesday’s game at Rogers Centre early after taking a fastball to his left wrist. The team initially diagnosed it as a left hand contusion.

Ryan Howard crunched a 448-foot home run among his three hits as the Phillies won for the seventh time in eight games, 4-2, over the Rockies at Coors Field on a chilly Thursday night.

Joe Mauer picked the right moment for his first home run of the season, ripping a solo shot to right field in the 13th inning and sending the Twins to a 4-3 win over the Pirates at PNC Park on Wednesday night.

A.J. Pollock stole a career-high three bases in Wednesday’s 6-1 win over the Marlins, including a swipe of home. It was part of a banner night for D-backs baserunners, who collected six steals.

Roenis Elias has pitched well all season, but that still has not translated into wins because the Mariners have struggled to get him runs. This time, Seattle got some early offense, and Elias did the rest, holding Baltimore scoreless into the eighth inning en route to a 4-1 victory.

The Cardinals’ offense continued to sizzle for a second straight night, smacking 14 hits to back Carlos Martinez in a 9-0 thumping of the Mets on Wednesday. New York starter Colon struggled for the third straight start, allowing 11 hits and nine runs (eight earned) over 4 1/3 innings.

The Rangers were hoping to get five innings out of starter Phil Klein on Wednesday night. That’s the most they have been getting from their other starters lately.

The D-backs ran their way to a 6-1 win over the Marlins on Wednesday night at Marlins Park to take the first three games of the four-game series. Arizona racked up six steals on the night, led by A.J. Pollock’s three, and Chase Anderson went eight-plus innings in his first victory of the season while handing Miami its sixth straight loss.